October 24, 2024

October 2024 Newsletter

News you can use

APS Beamline Commissioning Is Underway

The Advanced Photon Source (APS) upgraded storage ring is complete and the facility’s beamlines are in the process of returning to scientific operation. Every APS beamline will undergo operational, technical and scientific commissioning before restarting its general user program. Initial operations will be at a reduced current and availability as the machine is tuned up.

More Information

Employee spotlight

Thomas Sawyer, Ph.D. - Sr. Scientist - Structural Biology

Thomas provides x-ray diffraction, structural solutions, and molecular modeling services for Helix, having nearly a decade of experience between his academic training
and work in industry. He earned his Ph.D. in molecular and cellular biology from the University of Massachusetts Amherst, where he worked on expressing, purifying, and
characterizing challenging lysosomal glycoprotein complexes. Thomas has determined over a dozen novel protein structures and is also skilled in peptide drug discovery. In his free time, Thomas enjoys spending time with his family outdoors, including cycling, running, and stand-up paddling.

Featured services

MX Data Collection Service - Helix is a world leader in synchrotron X-ray data collection. We make it extremely simple to schedule your desired data collection using our booking website. Helix takes care of the entire process, including handling all the shipping logistics (including making shipping paperwork), synchrotron agreements/forms, and storage of raw/processed data. With over 50 years of combined synchrotron and industrial data collection experience, our customers rely on Helix for X-ray data collection and stick with us due to our quality, reliability, and continuous access to beamtime. We offer by-the-crystal pricing, so whether you have a few samples or hundreds per week, we can help with your x-ray data collection and help optimize your structure solution process.

Helix is hiring!!

Head of Structural Biology: We are looking to add an experienced Head of Structural Biology to our Indianapolis-based team. This role will manage and support the Helix team, planning & tracking all projects to produce high-quality work and support our client’s protein production, biophysical characterization, and structural biology projects.

Senior Scientist - Gene-to-Structure: We are looking to add an experienced senior scientist to join our Indianapolis-based team. This senior-level scientist will support our protein production and structural biology pipelines by producing proteins and setting up crystallization and/or cryo-EM experiments, interfacing with our clients, and writing technical project reports.

Apply Here

Helix highlights

Notre Dame Students Visited Helix!

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Helix BioStructures Hosted Notre Dame Esteem Graduate Students

Helix BioStructures recently welcomed around 50 students from Notre Dame’s ESTEEM graduate program, which focuses on business and entrepreneurship. CEO Joshua Carter gave an inspiring speech, encouraging students to embrace innovation and leadership in the evolving business landscape.

After the speech, the students toured our facilities to learn more about how Helix operates as a business in the biotech CRO industry. The visit was a great opportunity to showcase our company and share insights with future entrepreneurs. We look forward to continued engagement with academic programs.

Instrument review

Titan Krios G3i

The KRIOS G3i Cryo-Electron Microscope is a state-of-the-art instrument for visualizing biomolecules at high resolution. With its advanced optics and powerful electron detectors, the KRIOS G3i can capture detailed 3D images of proteins, nucleic acids, and other complex macromolecules, making it essential for structural biology research.

Known for its reliability and precision, the KRIOS G3i enables scientists to study molecular mechanisms critical to drug discovery and therapeutic development. Its automated loading and data collection systems allow for high-throughput sample analysis, ensuring both efficiency and accuracy. This makes the KRIOS G3i an indispensable tool for resolving even the most challenging biological structures and accelerating breakthroughs in life sciences.