February 2024 Newsletter
February 26, 2024
News you can use
RELION 5.0 beta release is now available to the public. RELION is a premier cryo-EM data processing suite that allows for high-resolution structure determination. Version 5.0 adds Blush, a machine-learning model for de-noising intermediate reconstructions that has the potential to lower the mass limit for high-resolution particle alignment (40 kDa!!!), and DynaMight, which uses machine learning to model and potentially undo per-particle molecular motions for improved reconstruction.
Employee Spotlight
Jungki Min, Ph.D. - Senior Scientist II
Jungki is a seasoned scientist with expertise in biochemistry, biophysics, and structural biology. His unwavering passion lies in unraveling the intricacies of atomic-level details through X-ray crystallography and Cryo-EM. Over decades, he has amassed a wealth of knowledge across academia, government, and industry, delving into diverse biological processes and mechanisms.
Featured Services
cryo-EM
Helix BioStructures is a leading provider of cryo-EM services. Equipped with four Thermo Scientific™ Titan Krios™ and three Glacios™ 2 microscopes, we are producing high-quality cryo-EM data at industrial speeds and at affordable rates. Importantly, we are able to purify the protein and go directly to grid preparation without freezing and thawing the protein. This leads to high quality particles and increased success for our clients. Contact us today to discuss how we can help you with your cryo-EM projects.
Helix Highlights
Lab Upgrade
Late last year we moved into a newly upgraded 6000 sq. ft. lab in Indianapolis, IN that we now call home.
With increased space, new scientists added to our team, and brand new equipment; we are excited to service more of our client’s needs and continue producing the high-quality research we are known for.Click the image see more photos of our move :)
Instrument review
ÄKTA pure
ÄKTA pure is a flexible and intuitive chromatography system for fast purification of proteins, peptides, and nucleic acids from microgram levels to tens of grams of target product. ÄKTA pure chromatography system is a reliable system where hardware and UNICORN software are designed to work together with columns and chromatography resins to meet purification challenges. Helix BioStructures is equipped with ÄKTA go and ÄKTA pure systems, provides customers with target purification services, and supports their crystallography and cryo-EM project needs. Contact us today to discuss how we can help you with your purification projects.